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1000 mcg 100 Tablets $17.49 Nature's Bounty Vitamin B-12 1000 mcg 100 Tablets $17.49 Vitamin B-12 aids in normal development and regeneration of red blood cells, and is involved in DNA synthesis and renewal

However, a defect in excretion of uric acid can also occur due to medications, such as diuretics, low dose aspirin, or alcohol

It can also metabolize analogs of NAD+, such as nicotinamide guanine dinucleotide (NGD+) and nicotinamide hypoxanthine dinucleotide (NHD+), generating cyclic compounds (cGDPR and cIDPR, respectively) with fluorescent properties, but lacking calcium-releasing activity [40]

This means most of a high-dose supplement remains in the gastrointestinal tract, though the direct link to digestive symptoms is not well established