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doi:10.3109/10837450.2014.979944 Evidence-Base Disclosure The published evidence base for GHK-Cu consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments

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When GHK-Cu exposure shifts gene-expression patterns in aging cells partway back toward a younger profile, the expression pattern movesbut the cell does not suddenly turn back its clock

Further transcriptome evaluation followed by RT-qPCR analysis allowed us to pin down several DEHP-induced functional enzymes involved in the metabolic process