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In terms of selecting the formulation delivery device, in a human study with a whole-virus influenza liquid vaccine without adjuvant, the immune response was better when using the breath-powered Bi-Directional OptiNose device and nasal drops in the delivery, rather than traditional nasal spray and an oral spray [22]

Ly PT, Wu Y, Zou H, Wang R, Zhou W, Kinoshita A, et al

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Thirty-four are indicated for at least two of the three conditions covered in this report, and seven indicated for all three, which reflects a gynaecological path dependency rather than causal commonalities between the conditions