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For a dog with early-to-moderate arthritis, thats potentially meaningful

Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

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[10] Selected BPC-157 studies have reported pro-angiogenesis-associated readouts in preclinical and cell-based systems, with published evidence more directly reporting VEGFR2-associated signalingincluding VEGFR2 expression, internalization, and downstream VEGFR2-Akt-eNOS pathway activationrather than broadly demonstrating upregulated VEGF transcription or secretion across all models