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Additionally, sterile water is hypotonic (lower solute concentration than many biological fluids), which may affect certain laboratory experiments if used improperly without buffering or proper formulation

The 0.9% benzyl alcohol preservative allows the vial to be accessed multiple times over 28 days while maintaining sterility, unlike single-use sterile water

Despite the intestinal barrier being designed to limit the translocation of luminal components, certain factors disrupt its integrity including genetic predisposition, gut microbiota dysbiosis and environmental factors such as those present in food and oral therapeutics (Fig

This single protein, made only by stomach parietal cells, is the key that unlocks B12 absorption
