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Loss of either subunit eliminates MPC activity, and liver-specific ablation of the MPC diminishes liver damage and inflammation in mice on obesogenic diets (Gray et al., 2015

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Cortisol increases the expression of genes for metallothionein and ZIP-14, which accumulate zinc in the liver and adipose tissue, promoting hypozincemia in obese people (157)

found that dynamic data analysis significantly enhanced the evaluation of the therapeutic effects of drugs targeting tumor Gln metabolism (73, 74)
