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Administration of dilute acetylcysteine solutions may minimize the tendency of the drug to aggravate vomiting
Increased approaches to killing cancer cells have been investigated by obstructing different metabolic pathways in tumors (Altman et al., 2017
Although GSH is not alone responsible for these protective mechanisms, the hepatic production of GSH seems to be essential to survival, with knockout mice dying within months secondary to inflammation and hepatic steatosis resulting in liver failure [21]
Furthermore, these nanocarriers are capable of depleting GSH levels in the tumor microenvironment to augment stress on cells and induce cell death pathways, including ferroptosis, making cancer cells sensitive to treatment Fig
