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While there is no corroborative clinical trial data, animal experiments suggest that hydroxocobalamin produces a time and organdependent, selective regulation of nitric oxide synthases during endotoxemia and regulates downstream inflammatory mediators, thereby having a potential role in the treatment septic shock 4
Weiyu Zhao and Xueling Wang designed animal experiments and pathologic analysis
Generalizability The findings of this economic analysis cannot be generalized to all patients with vitamin B12 deficiency
