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In AR-positive cells such as LNCaP, MYC also upregulates ASCT2 expression and enhances glutamine uptake in an androgen-responsive manner (39)

While numerous synthetic ARIs have demonstrated excellent inhibition and shown promising results in animal studies, their efficacy in clinical trials was not very encouraging with some ARIs exhibiting adverse side effects

Integrated analysis of microbiome and transcriptome reveals the mechanisms underlying the chlorogenic acid-mediated attenuation of oxidative stress and systemic inflammatory responses via gut-liver axis in post-peaking laying hens