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JAMA 265:888892 Nishad R, Mukhi D, Tahaseen SV, Mungamuri SK, Pasupulati AK (2019) Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy

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The once-daily dose is less nephrotoxic than the multiple daily dosing in children, in term of a lower rise of creatinine over baseline [137,138]
