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Its targeted behaviour has made it of interest in studies investigating cellular energetics, enzymatic regulation, and responses to metabolic stress in in-vitro environments

In contrast, LDHB KD, alone or in combination with Erastin or SSZ, failed to apparently affect STAT3, SCD1, C-MYC, or acyl-CoA synthetase long-chain family member 4 (ACSL4), which have been reported to context- dependently regulate ferroptosis [4649] ( Supplementary Figure 6f )

Biomaterials 288 , e2307796121 (2022)

Therapeutically, oral administration of GSNO was found to be most effective in reducing intraocular inflammation and bacterial burden