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Furthermore, the presence of comorbidities profoundly alters the baseline redox state and inflammatory milieu, influencing MIRI severity and therapeutic response

Enhanced intracellular reactive oxygen species by photodynamic therapy effectively promotes chemoresistant cell death
Intracellular ROS measurement LNCaP cells were seeded at 6 10 4 cells/well in 24-well plates, adhered overnight and then incubated with conditioned media for 2.5 days before treatment with doxorubicin or taxol
