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The most common adverse reactions in patients with sickle cell disease or other anemias (incidence 6%) are pyrexia, abdominal pain, bone pain, headache, vomiting, pain in extremity, sickle cell anemia with crisis, back pain, ALT increased, AST increased, arthralgia, oropharyngeal pain, nasopharyngitis, neutrophil count decreased, cough and nausea

doi: 10.1083/jcb.142.1.117

Although numerous preclinical and animal studies have provided evidence linking trained immunity to inflammatory diseases, several critical issues remain unresolved

Minireview: Thioredoxin-interacting protein: regulation and function in the pancreatic beta-cell