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Critically, AOD-9604 did not produce the metabolic side effects associated with full-length growth hormone, including no insulin resistance or glucose intolerance, no elevation of IGF-1 levels, no fluid retention or joint pain, and no cardiovascular parameter changes

Heart health may improve with a B12 supplement

Therefore, targeting CD38 remains an attractive strategy for cancer treatment in hematological malignancies as well as in solid tumors

Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist that was originally developed for type 2 diabetes management and subsequently approved by the FDA for chronic weight management under the brand name Wegovy