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Front Immunol 11:783 Hsieh C-H et al (2021) An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment

Nuclear factor erythroid 2-related factor 2 (Nrf2) can reduce ferroptosis through stimulating the typical ferroptosis target genes expressions, such as ferritin heavy chain 1 (FTH1), quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1)
The secondary antibodies were HRP-conjugated Affinipure Goat Anti-Mouse IgG(H + L) (1:10,000, Proteintech, SA00001-1) and HRP-conjugated Affinipure Goat Anti-Rabbit IgG(H + L) (1:10,000, Proteintech, SA00001-2)
Low doses of orally administered CBD (20 or 30 mg/day) had no beneficial analgesic effect on pain associated with osteoarthritis or psoriatic arthritis in a double-blind placebo-controlled trial in 136 subjects [93]
