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A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer

In fact, other researchers have even stated that abnormal expression of any of these DHT metabolizing enzymes (3-HSD, 3-HSD, or even 17-HSD) might increase scalp DHT and possibly even accelerate the balding process

The COMT connection: Another enzyme affected by poor methylation is COMT (catechol-O-methyltransferase), which breaks down and clears neurotransmitters like dopamine and adrenaline
The peptides ability to modulate cytoskeletal organization directly influences cellular motility, which is fundamental to tissue regeneration processes
