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Several lines of evidence have suggested that endothelial function is impaired as blood pressure increases and that the degree of dysfunction is related to the magnitude of blood pressure elevation, 64, 65 indicating that endothelial dysfunction is a consequence of hypertension

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When evaluated together in experimental environments, these peptides provide researchers with a framework for studying synergistic biological pathways associated with regenerative signaling, extracellular matrix regulation, and angiogenic activity