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Network analysis revealed several metabolites exhibiting high connectivity, including S-adenosylhomocysteine, 5-methylthioadenosine, and diaminopimelic acid, reflecting their central roles within metabolic pathways rather than differential abundance between groups (Fig

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Abstract The androgen receptor (AR) signalling pathway has been intensively studied in the context of prostate cancer, where androgen deprivation therapy is part of the standard of care for metastatic disease

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