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These treatments are similar to dialysis, because a patients blood is sent through a machine to remove different substances

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Simplistically, when cholesterol in the plasma membrane is in excess for any reason, e.g., after LDL uptake by receptor-mediated endocytosis, there is a rise in accessible (or 'active') cholesterol, some of which is transferred to the nascent HDL, but much is returned to the endoplasmic reticulum to switch off cholesterol biosynthesis and expression of the LDL receptor