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Pfizer purchased exclusive global commercialization rights for the then-experimental treatment in December 2014 for $295 million upfront and a promise of up to $275 million in milestones

Activated macrophages not only increase MG production, they also down-regulate expression of their own glyoxalase enzymes, which may contribute to the inflammatory response [28] and may suggest a role for MG as an antimicrobial strategy

Inducible flavone in oats ( Avena sativa ) is a novel defense against plant-parasitic nematodes