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16 However, it is argued that this might lead to unnecessary intervention and could be limited to patients with moderate to severe symptoms

Neurobiological Research A growing body of published research has examined this compounds interactions with dopaminergic, serotonergic, and GABAergic neurotransmitter systems in animal research models

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Cell activation leads to the liberation of arachidonic acid from membrane phospholipids, and 5-LO converts arachidonate to LTA4, with 5-LO activating protein as a cofactor