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10.1515/BC.2003.059 7

1E), and significant rise in intracellular ROS and lipid peroxidation in thyroid cancer cells in vitro

Although a direct causal relationship between the copper toxicity and the formation of PA or PHA is lacking, studies by high-performance thin-layer chromatography and MALDI-TOF-MS (Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry) have revealed an increased level of PA and PHA in the liver mitochondria of ATP7b / mice but not the wild-type control mice [53]

Khoronenkova SV, Dianova II, Ternette N, Kessler BM, Parsons JL, Dianov GL
