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Inflammatory mediators, such as interleukin-6 (IL-6) and tumor necrosis factor- (TNF-), promote osteoclastogenesis
[84] treated 1.5-cm segmental defects in rabbits with an OGP incorporated in a PLGA scaffold

Long-term use sustains results, preventing rebound pigmentation when paired with sunscreen and antioxidants

[Crossref] Siesj BK, Zhao Q, Pahlmark K, Siesj P, Katsura K, et al
