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Description
It promotes inflammation via NF-B pathway activation (82) and by activating the NLRP3 inflammasome in endothelial cells and arterial walls in mice, involving mitochondrial ROS, TXNIP, and lysosomal instability (101, 134)

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BJD 2016

to increase fertility and to recover normal Hypothalamus-Pituitary-Testes/Adrenal-Axis (HPTA / HPAA) function after using AAS or SARMs, 2ND