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BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality

Swiss Target Prediction 8 and SEA Search Server 9 were employed to identify the ingredient-related target proteins according to the determined main active ingredients

Notably, a small cell lung carcinoma cell line, which expresses POMC and ACTH, possesses a hypomethylated POMC promoter, suggesting that ectopic ACTH secretion by tumors may be due to hypomethylation at a relatively early stage in carcinogenesis (41)
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