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Melatonin supplementation (3 mg/day) has been shown to improve objective and subjective sleep quality, increase 6-sulfatoxymelatonin levels, and enhance total antioxidant capacity in FM patients, suggesting dual chronobiotic and antioxidant benefits (31)
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Multinucleated myofiber apoptosis is distinct from mononucleated cell apoptosis, which results in the complete loss of the cell's nucleus, but does not always lead to cell death
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