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Furthermore, MEK inhibitor induces the melanoma cells to enter the dedifferentiation state through the loss of microphthalmia-associated transcription factor (MITF) [91,92,93,94], while HER2-targeted therapy drives breast cancer cells toward luminal-like or mesenchymal-like pre-DTP states [78]

Nirenberg M

This angiogenic effect is considered one of the primary reasons BPC-157 is grouped within the regenerative research category, as improved local blood supply is mechanistically relevant to a range of tissue-repair-adjacent research questions

10.5306/wjco.v7.i1.106 53 KischkelF
