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[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Mongioi L, Calogero AE, Vicari E, Condorelli RA, Russo GI, Privitera S, et al

Gary Goldfaden, MD, is a clinical dermatologist and lifetime member of the American Academy of Dermatology

Nat Sci Sleep

Translational studies using exosomes showed a relationship between the epigenetic modulation of glutamatergic function and a brain metabolic dysfunction known as insulin resistance (IR) as showed by an increase and sex-specific phosphorylation in the expression of IRS1, a key marker of the insulin signaling cascade, in discrete exosomes enriched for the neural cell adhesion molecule L1 (L1CAM), a protein highly expressed in the brain [52, 70,71,72]