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Experimental models have demonstrated that AKI can lead to chronic damage of renal parenchyma, resulting in CKD, indicating that early intervention may impact long-term outcomes (151)

It will be interesting to investigate whether up-regulated TH-DA pathway functions and increased DA generation and oxidation can be identified in early stage of high-risk populations, such as LRRK2 or PINK1 mutation healthy carriers

Frias, MD , medical director and principal investigator at Velocity Clinical Research in Los Angeles, said during a presentation

Safety and Efficacy of Combined Resveratrol and Sirolimus in Lymphangioleiomyomatosis
