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They take part in the regulation of the redoxsensitive transcription factors, including NRF2/Kelchlike ECHassociated protein1 (NRF2/KEAP1) and nuclear factor kappaB (NFB), which are regarded as the integral regulators of a wide range of biological processes (Figure 3)
The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction
