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In severe COVID-19 or acute respiratory distress syndrome (ARDS), an mRNA therapy delivered to the lung could, in theory, provide a therapeutic protein (for example, an anti-inflammatory cytokine or a soluble receptor to neutralize inflammatory signals) right at the site of injury
In return, EpCAM as a human TAA can cause tumor immune evasion via Th2 responses development [49]
10.1016/j.brainresbull.2021.06.014 99 PetratF.RauenU.GrootH
