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During the early stages of acute pancreatitis, the inflammatory response damages the intestinal barrier, allowing bacteria and endotoxins to enter the blood, triggering an inflammatory storm, sepsis, and even multiple organ failure [92]

doi:10.1016/j.str.2008.06.013

Posttraumatic leakage of electrons across the inner mitochondrial membrane drives free radical formation shortly after injury, which further damages cell membranes and nucleic acids

Inhibitory effect of edaravone on systemic inflammation and local damage in skeletal muscles following long-term ischemia to murine hind limb
