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Description
The compounds quinolinium scaffold confers membrane permeability that enables intracellular enzyme inhibition, distinguishing it from earlier polar NNMT inhibitor scaffolds that did not effectively enter intact cells

No, AOD-9604 is not FDA-approved for human therapeutic use

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Physiological activation of brown fat 3-AR through cold stress, (96-98) or direct pharmacological activation (99) rapidly activates non-shivering thermogenesis
