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It is one of the important amino acids that increases energy and lean muscle mass

low neonatal vitamin B-12 concentrations were associated with LBW (13)

Finally, the above approach to evaluate organoid-derived FVII function suggests that although these experiments are not specific for FVII activity per se, supernatants (supplemented with vitamin K) show hemostatic potential due to the secretion of serine proteases (probably gamma-carboxylated) into the conditioned medium that mimic the FVII effect

This distinction is particularly useful in experimental designs where separation of adipose-specific signaling from systemic endocrine effects is required