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94 , 95 Soon afterwards, the nuclear membrane loses integrity, leading to the release of chromatin into the cytosol and subsequently the final form NETs

Zorn, J

The primary etiology of VaD is linked to cerebrovascular pathology, leading to chronic cerebral hypoperfusion (CCH), which reduces cerebral blood flow and nutrient supply, while promoting the accumulation of harmful molecules in the brain

The underlying biochemical lesion is a reduction in the activity of lipoprotein lipase, and the disorder is transmitted as an autosomal recessive gene
