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Mauras N, Gonzalez de Pijem L, Hsiang HY, Desrosiers P, Rapaport R, Schwartz ID, et al .: Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years
Since there is no response to hormonal therapy or HER2-targeted drug therapies, chemotherapy remains one of the main treatment options, yet the prognosis remains poor due to high recurrence rates and drug resistance (Won and Spruck 2020, An et al

Currently developments are the nano-filtration, ozonation and power activated carbon

Snow RW, Craig M, Deichmann U, Marsh K
