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Abbreviations ALS: Amyotrophic lateral sclerosis CCS: Copper chaperone for SOD1 CSF: Cerebrospinal fluid ISF: Interstitial fluid non- SOD1 ALS: Amyotrophic lateral sclerosis without mutations in the SOD1 gene PD: Parkinsons disease PSP: Progressive supranuclear palsy SOD1: Cu/Zn-superoxide dismutase SOD1 -ALS: Amyotrophic lateral sclerosis with mutations in the SOD1 gene References Andersen PM, Al-Chalabi A

Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae

No existing drugs have extensive effects on symptoms that develop in the later stages of this disease, such as postural instability, dysphagia, dysphonia, dyskinesias, as well as constipation [45]

Some patients use BPC-157 throughout their semaglutide therapy