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Acknowledgements This work was partially supported by the National Research Programs from Ministry of Science and Technology (MOST) of China (2016YFA0201200), the National Natural Science Foundation of China (51525203, 81403120, and 31300824), Collaborative Innovation Center of Suzhou Nano Science and Technology, a 111 program from the Ministry of Education (MOE) of China, and a Project Funded by the Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions

The chest x-ray shows hyperinflation of the left lung, widened intercostal spaces, and a rightward mediastinal shift, indicating a ball-valve obstruction from foreign body aspiration that causes hypoxemia via a ventilation-perfusion mismatch

Hu X, Fujimoto J, Ying L, Fukuoka J, Ashizawa K, Sun W, Reuben A, Chow CW, McGranahan N, Chen R, Hu J, Godoy MC, Tabata K, Kuroda K, Shi L, Li J, Behrens C, Parra ER, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Kadara H, Scheet P, Roarty E, Ostrin EJ, Wang X, Carter BW, Antonoff MB, Zhang J, Vaporciyan AA, Pass H, Swisher SG , Heymach JV, Lee JJ, Wistuba II, Hong WK, Futreal PA, Su D, Zhang J