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Glutathione peroxidase-1 (GPx-1), a selenium-dependent enzyme, catalyzes the reduction of peroxides using GSH as the electron donor (2 GSH + HO GSSG + 2 HO)

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it plays essential roles in virtually all cellular processes, ranging from basic metabolism to signaling in development and disease

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PMC 4336627

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FASEB J 8 : 11311138

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