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doi: 10.1183/13993003.01328-2016 170 PettigrewM
Beyond its role in RA, infliximab has demonstrated potential in preventing tumor-induced bone metastasis by reducing the viability of metastatic breast cancer cells (e.g., MDA-MB-231) and effectively inhibiting breast cancer bone metastasis in mouse models (89)
Blocking MLCK1 recruitment to the tight junction limits tight junction barrier loss without interfering with essential MLCK functions in epithelial cells and cells of other types
