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doi: 10.1093/jnci/djt315 241

[DOI] [PubMed] [Google Scholar] 178.Nandan P, Nirupama M, Nayanatara Arun K, Bhagyalakshmi K, Jyoti Ramnath K, Roopesh P

First, the ROS surge triggered by M5 oxidizes cardiolipin, loosening respiratory chain super complexes and sensitizing the mitochondrial permeability transition pore (mPTP) to opening [13, 14]

The latter lowers the strain on the joints
