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doi: 10.3389/fneur.2019.00894

Riederer P, Nagatsu T, Youdim MBH, Wulf M, Dijkstra JM, Sian-Huelsmann J

The iron overload-induced oocyte damage and embryo toxicity might be related to ferroptosis mediated by multiple signaling pathways, including nuclear receptor coactivator 4-dependent ferritinophagy (123), glutathione peroxidase 4-dependent downregulation (124), and heme oxygenase 1 (HMOX1) overexpression (120), in which mitochondrial dysfunction and structural damage play a central role

doi: 10.1016/j.clim.2023.109687 8 Hiam-GalvezKJAllenBMSpitzerMH
