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[DOI] [PubMed] [Google Scholar] 272.Wu CW, Dionigi G, Barczynski M, Chiang FY, Dralle H, et al
Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice
The gene encodes MTHFR, a cytosolic flavoprotein that catalyzes the reduction of 5,10-methylene-THF to 5-methyl-THF, thereby associating the folate and methionine cycles
J Biol Chem 285:58155826
