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They are easy to prepare, nonimmunogenic and show good aerosolization in solid form

Y.SenthilkumarA.KandhanK.SubramanianR.KizhakkayilJ.RamachandranT.et al (2024)

The metabolic stress of early lactation cows often derives from Gram-negative bacterial mastitis when the blood-milk barrier is disrupted by inflammatory mediators, or from the gastrointestinal bacterial load when the epithelial barrier is disrupted due to subacute ruminal acidosis or leaky gut induced by heat stress or other challenges [9]

When properly packaged (e.g., in sealed glass vials), they can withstand short-term temperature fluctuations without signs of degradation