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The expression of S100A9 in neutrophiles and activated macrophages, cells that produce large amounts of ROS during inflammation, suggests that it protects tissues from oxidative damage (Srikrishna, 2012)

However, unlike glucose and part of amino acids, excessive cholesterol uptake by CD8 + T and CD4 + T cells inhibits their function

J.van GeldermalsenM.GaoD.FazliL.et al (2015a)