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Description
Modifier 59 and CPT 96372: When and How to Use It Modifier 59 signals a "Distinct Procedural Service." Use it with 96372 when a second or subsequent injection is given at the same visit, involving a different drug administered at a different anatomical site

Its selectivity for NNMT (IC50 values in the low micromolar range) means it increases NAD+ by preserving nicotinamide availability rather than directly supplementing NAD+ precursors

It will depend on the individuals needs

10.1186/s12877-015-0060-x [DOI] [PMC free article] [PubMed] [Google Scholar] Rizzo N
