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This reversal was seen also on the background of the disturbed prostaglandins- and NO-systems, prostaglandins synthesis inhibition as well as NO-overstimulation (NOS-substrate L-arginine) or NO-blockade (N(G)-nitro-L-arginine methyl ester (L-NAME)) (Stupnisek et al., 2012

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Immediately prior to application, the lyophilized digest was reconstituted and neutralized on ice to 7.4 pH at an ECM concentration of 10, 20, and 40 mg of ECM/mL

Concomitant use of other paracetamol-containing products or use of other cold and cough medicines, including cough suppressants and sympathomimetics (decongestants, appetite suppressants and amphetamine-like psychostimulants), should be avoided