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[DOI] [PubMed] [Google Scholar] 155.Erkkola M., Kaila M., Nwaru B.I., Kronberg-Kippil C., Ahonen S., Nevalainen J., Veijola R., Pekkanen J., Ilonen J., Simell O., et al

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Decreased expression of GPx1, due to the cellular accumulation of S-adenosylhomocysteine, was found to promote oxidative stress, as hydrogen peroxide release from cells (measured by Amplex Red) as well as intracellular hydrogen peroxide production (measured by Hyper, a live-cell hydrogen peroxide probe) were enhanced by exposure of endothelial cells to increased amounts of S-adenosylhomocysteine