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Immune cellsparticularly lymphocytes and macrophagesmaintain high intracellular GSH concentrations to sustain proliferation and cytokine production
In the rodent the hypothalamic connectivity involved in feeding develops during the second week postnatally ( in utero growth restriction or with obese or hyperleptinemic dams, can also disrupt this connectivity and result in a subsequent insensitivity to satiety signals (Yura et al., 2005
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