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Although there is restricted exchange between the cytoplasmic and mitochondrial pools of THF molecules, these compartments are metabolically connected by transport of the one-carbon donors (serine, glycine, and formate) across the mitochondrial membranes

The enrollment target is 300, and the study assesses both the procedure's effect on intraocular pressure and how long that effect lasts

NSRAEM here
Castagliuolo et al